Our favorite question! Ideally, take a hot shower and use regular bath soap. For a quick fix, mix sugar with hand lotion or use a body scrub to exfoliate it off. If you still have some dye left on your hands and want it off immediately, then you could apply a cleanser (such as Comet) on a brush with a little water. A second wash in clean soapy water will ensure that no cleanser remains on your hands to dry or damage the skin.